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. 2016 Feb 2;12(1):55–67. doi: 10.5114/aoms.2016.57580

Table IX.

Prevalence of concurrent CKD complications among participants whose preserved eGFRcr was confirmed versus not confirmed using eGFRcys stratified by age

Parameter < 65 years 65 to 79 years ≥ 80 years P-value
Preserved eGFRcr not confirmed using eGFRcys Preserved eGFRcr confirmed using eGFRcys P-value Preserved eGFRcr not confirmed using eGFRcys Preserved eGFRcr confirmed using eGFRcys P-value Preserved eGFRcr not confirmed using eGFRcys Preserved eGFRcr confirmed using eGFRcys
Number of participants: 847 12,534 1,899 7,930 572 687
 Hypertension 77.6% 49.3% < 0.001 73.5% 59.5% < 0.001 64.7% 62.4% 0.42
 Serum albumin < 3.8 g/dl 19.4% 7.0% < 0.001 18.1% 9.6% < 0.001 20.0% 15.4% 0.07
 Anemia 23.5% 9.2% < 0.001 20.6% 11.3% < 0.001 23.3% 15.1% 0.008
 hsCRP > 3 mg/l 64.5% 39.8% < 0.001 50.9% 34.5% < 0.001 43.2% 26.1% < 0.001
 ACR > 30 mg/g 25.9% 9.5% < 0.001 22.6% 11.8% < 0.001 23.9% 15.3% 0.001

ACR – albumin: creatinine ratio, CKD – chronic kidney disease, eGFR – estimated glomerular filtration rate, hsCRP – high sensibility C-reactive protein. Preserved eGFRcr confirmed using eGFRcys was defined as eGFRcr and eGFRcys ≥ 60 ml/min/1.73 m2. Preserved eGFRcr not confirmed using eGFRcys was defined as eGFRcr ≥ 60 ml/min/1.73 m2 and eGFRcys < 60 ml/min/1.73 m2. Equations for eGFRcr and eGFRcys are shown in Table I. Hypertension was defined as systolic blood pressure ≥ 140 mm Hg, diastolic blood pressure ≥ 90 mm Hg, or self-reported use of antihypertensive medications. Anemia was defined as hemoglobin concentration < 13.0 g/dl and < 12.0 g/dl for males and females, respectively [15].