Table IX.
Parameter | < 65 years | 65 to 79 years | ≥ 80 years | P-value | |||||
---|---|---|---|---|---|---|---|---|---|
Preserved eGFRcr not confirmed using eGFRcys | Preserved eGFRcr confirmed using eGFRcys | P-value | Preserved eGFRcr not confirmed using eGFRcys | Preserved eGFRcr confirmed using eGFRcys | P-value | Preserved eGFRcr not confirmed using eGFRcys | Preserved eGFRcr confirmed using eGFRcys | ||
Number of participants: | 847 | 12,534 | 1,899 | 7,930 | 572 | 687 | |||
Hypertension | 77.6% | 49.3% | < 0.001 | 73.5% | 59.5% | < 0.001 | 64.7% | 62.4% | 0.42 |
Serum albumin < 3.8 g/dl | 19.4% | 7.0% | < 0.001 | 18.1% | 9.6% | < 0.001 | 20.0% | 15.4% | 0.07 |
Anemia | 23.5% | 9.2% | < 0.001 | 20.6% | 11.3% | < 0.001 | 23.3% | 15.1% | 0.008 |
hsCRP > 3 mg/l | 64.5% | 39.8% | < 0.001 | 50.9% | 34.5% | < 0.001 | 43.2% | 26.1% | < 0.001 |
ACR > 30 mg/g | 25.9% | 9.5% | < 0.001 | 22.6% | 11.8% | < 0.001 | 23.9% | 15.3% | 0.001 |
ACR – albumin: creatinine ratio, CKD – chronic kidney disease, eGFR – estimated glomerular filtration rate, hsCRP – high sensibility C-reactive protein. Preserved eGFRcr confirmed using eGFRcys was defined as eGFRcr and eGFRcys ≥ 60 ml/min/1.73 m2. Preserved eGFRcr not confirmed using eGFRcys was defined as eGFRcr ≥ 60 ml/min/1.73 m2 and eGFRcys < 60 ml/min/1.73 m2. Equations for eGFRcr and eGFRcys are shown in Table I. Hypertension was defined as systolic blood pressure ≥ 140 mm Hg, diastolic blood pressure ≥ 90 mm Hg, or self-reported use of antihypertensive medications. Anemia was defined as hemoglobin concentration < 13.0 g/dl and < 12.0 g/dl for males and females, respectively [15].