Table II.
Clinical predictors associated with warfarin use
| Parameter | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Age ≥ 75 years | 0.60 (0.48–0.75) | < 0.001 | 0.54 (0.43–0.69) | < 0.001 |
| Gender, female | 1.15 (0.93–1.41) | 0.202 | 1.12 (0.90–1.39) | 0.317 |
| Heart failure | 0.99 (0.80–1.21) | 0.902 | 1.12 (0.90–1.39) | 0.305 |
| Hypertension | 1.34 (1.08–1.65) | 0.007 | 1.43 (1.14–1.79) | 0.002 |
| Diabetes | 1.47 (1.04–2.11) | 0.031 | 1.43 (0.99–2.07) | 0.056 |
| Prior stroke/TIA/TE | 1.55 (1.15–2.07) | 0.004 | 1.59 (1.18–2.16) | 0.003 |
| Coronary artery disease | 0.60 (0.47–0.77) | < 0.001 | 0.62 (0.48–0.80) | < 0.001 |
| Peripheral artery disease | 0.15 (0.02–1.24) | 0.079 | 0.15 (0.02–1.24) | 0.078 |
CI – confidence interval, OR – odds ratio, TE – thromboembolism, TIA – transient ischemic attack.