Table 3.
Clinical variables.
| Variable | Controls | OCHOs | P |
|---|---|---|---|
| SCBFv at supine, cm/s (100%) | 104.2 ± 18.1 | 104.3 ± 19.7 | 0.974 |
| SCBFv drop from supine at 1st minute of tilt, % of baseline | 96.8 ± 5.0 | 86.5 ± 8.8 | <0.0001 |
| SCBFv drop from supine at 5th minute of tilt, % of baseline | 96.7 ± 6.3 | 81.8 ± 8.1 | <0.0001 |
| SCBFv drop from supine at 10th minute of tilt, % of baseline | 95.3 ± 5.0 | 77.5 ± 7.8 | <0.0001 |
| MCBFv at supine, cm/s (100%) | 65.1 ± 10.9 | 65.1 ± 11.8 | 0.967 |
| MCBFv drop from supine at 1st minute of tilt, % of baseline | 97.9 ± 4.5 | 84.8 ± 8.9 | <0.0001 |
| MCBFv drop from supine at 5th minute of tilt, % of baseline | 98.1 ± 6.6 | 79.6 ± 8.6 | <0.0001 |
| MCBFv drop from supine at 10th minute of tilt, % of baseline | 95.8 ± 5.6 | 75.9 ± 8.2 | <0.0001 |
| DCBFv at supine, cm/s (100%) | 45.5 ± 9.5 | 45.3 ± 9.7 | 0.879 |
| DCBFv drop from supine at 1st minute of tilt, % of baseline | 99.4 ± 7.6 | 83.3 ± 13.1 | <0.0001 |
| DCBFv drop from supine at 5th minute of tilt, % of baseline | 98.8 ± 8.2 | 77.9 ± 13.1 | <0.0001 |
| DCBFv drop from supine at 10th minute of tilt, % of baseline | 96.5 ± 8.7 | 73.7 ± 12.5 | <0.0001 |
| SBP supine, mmHg | 122.9 ± 15.1 | 122.6 ± 14.6 | 0.895 |
| SBP at first minute of tilt, mmHg | 123.2 ± 15.4 | 122.2 ± 14.7 | 0.643 |
| SBP at fifth minute of tilt, mmHg | 122.6 ± 15.4 | 121.3 ± 14.9 | 0.532 |
| SBP at 10th minute of tilt, mmHg | 121.6 ± 13.9 | 119.9 ± 14.8 | 0.412 |
| MBP supine, mmHg | 91.1 ± 9.4 | 90.5 ± 10.6 | 0.620 |
| MBP at 1st minute of tilt, mmHg | 93.2 ± 10.1 | 93.3 ± 10.4 | 0.995 |
| MBP at 5th minute of tilt, mmHg | 93.2 ± 10.5 | 91.9 ± 9.7 | 0.365 |
| MBP at 10th minute of tilt, mmHg | 92.1 ± 9.6 | 90.4 ± 9.7 | 0.200 |
| DBP supine, mm Hg | 75.2 ± 7.6 | 74.5 ± 9.8 | 0.560 |
| DBP at 1st minute of tilt, mmHg | 78.3 ± 8.5 | 78.4 ± 8.9 | 0.923 |
| DBP at 5th minute of tilt, mmHg | 78.2 ± 9.3 | 77.1 ± 8.7 | 0.391 |
| DBP at 10th minute of tilt, mmHg | 77.1 ± 8.40 | 75.5 ± 8.45 | 0.187 |
| HR supine, BPM | 71.8 ± 11.9 | 72.5 ± 11.8 | 0.672 |
| HR at 1st minute of tilt, BPM | 78.6 ± 13.2 | 81.0 ± 13.9 | 0.209 |
| HR at 5th minute of tilt, BPM | 81.3 ± 12.5 | 84.0 ± 13.9 | 0.144 |
| HR at 10th minute of tilt, BPM | 82.5 ± 12.5 | 85.8 ± 15.2 | 0.09 |
| End tidal CO2 supine, mmHg | 40.5 ± 2.70 | 40.1 ± 2.44 | 0.45 |
| End tidal CO2 at 1st minute of tilt, mmHg | 39.5 ± 2.01 | 39.4 ± 2.1 | 0.714 |
| End tidal CO2 at 5th minute of tilt, mmHg | 38.9 ± 2.05 | 38.9 ± 2.1 | 0.985 |
| End tidal CO2 at 10th minute of tilt, mmHg | 38.7 ± 1.15 | 38.5 ± 2.1 | 0.614 |
| Resistance index supine | 0.56 ± 0.08 | 0.56 ± 0.08 | 0.909 |
| Resistance index at 1st minute of tilt | 0.54 ± 0.08 | 0.57 ± 0.08 | 0.0045 |
| Resistance index at 5th minute of tilt | 0.54 ± 0.08 | 0.58 ± 0.08 | 0.0029 |
| Resistance index at 10th minute of tilt | 0.55 ± 0.01 | 0.58 ± 0.09 | 0.01 |
| CVR supine, mmHg/cm/s | 1.44 ± 0.31 | 1.45 ± 0.31 | 0.861 |
| CVR at 1st minute of tilt, mmHg/cm/s | 1.49 ± 0.31 | 1.76 ± 0.40 | <0.0001 |
| CVR at 5th minute of tilt, mmHg/cm/s | 1.50 ± 0.30 | 1.85 ± 0.45 | <0.0001 |
| CVR at 10th minute of tilt, mmHg/cm/s | 1.52 ± 0.32 | 1.92 ± 0.43 | <0.0001 |
Data are mean ± SD. Percentages are expressed as percent of baseline where baseline is equal to 100%. OCHOs, orthostatic cerebral hypoperfusion syndrome; SCBFv/MCBFv/DCBFv, systolic/mean/diastolic cerebral blood flow velocity; SBP/MBD/DBP, systolic/mean/diastolic blood pressure; HR, heart rate, CVR, cerebral vascular resistance.