Table 3.
Study | Subjects | Study Design | Anodal Site | Cathodal Site | Stimulation Intensity | Number of sessions | Primary Outcome | Findings |
---|---|---|---|---|---|---|---|---|
A | ||||||||
Fregni et al., 2008 | n = 23, HC with urges to eat | Sham-controlled, crossover | R-DLPFC | L-DLPFC | 2 mA, 20 min | 1 | Craving VAS, food consumption | Reduced craving in active tDCS, less consumption |
Goldman et al., 2011 | n = 19, HC with urges to eat | Sham-controlled, crossover | R-DLPFC | L-DLPFC | 2 mA, 20 min | 1 | Craving VAS, Resist food | Reduced craving, increased ability to resist food |
Kekic et al., 2014 | n = 20, HC with urges to eat | Sham-controlled, crossover | R-DLPFC | L-DLPFC | 2 mA, 20 min | 1 | Craving VAS | Reduced craving for sweet foods |
Lapenta et al., 2014 | n = 9, HC with urges to eat | Sham-controlled, crossover | R-DLPFC | L-DLPFC | 2 mA, 20 min | 1 | Cue-induced food craving | Reduced food intake |
B | ||||||||
Khedr et al., 2014 | n = 7, AN | Open-Label | L-DLPFC | N/A | 2 mA, 25 min | 10, daily | EDI and EAT | Significant effect of time on EAT and EDI |
A, tDCS studies related to food addiction and urges to eat; B, tDCS studies related to AN.
AN, anorexia nervosa; HC, healthy controls; EAT, eating attitudes test; EDI, eating disorder inventory; L-DLPFC, left dorsolateral prefrontal cortex; R-DLPFC, right dorsolateral prefrontal cortex; tDCS, transcranial direct current stimulation; VAS, visual analog scale.