Table 2.
Multivariable analyses of post-TACE survival.
| Univariate | Multivariable | |||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | p value | Hazard ratio | 95% CI | p value | |
| Age | 0.99 | (0.98, 1.01) | 0.500 | 1.00 | (0.98, 1.02) | 0.721 |
|
| ||||||
| Gender | 0.295∗∗ | 0.167∗∗ | ||||
| Male | 1.00 (reference) | (—, —) | 1.00 (reference) | (—, —) | ||
| Female | 1.23 | (0.84, 1.79) | 0.295 | 1.35 | (0.88, 2.06) | 0.167 |
|
| ||||||
| Race | 0.108∗∗ | 0.132∗∗ | ||||
| White | 1.00 (reference) | (—, —) | 1.00 (reference) | (—, —) | ||
| Black | 0.88 | (0.58, 1.36) | 0.75 | (0.47, 1.19) | 0.222 | |
| Other | 1.91 | (0.99, 3.68) | 1.57 | (0.80, 3.08) | 0.194 | |
|
| ||||||
| Child-Pugh | <0.0001∗∗ | <0.0001∗∗ | ||||
| A | 1.00 (reference) | (—, —) | 1.00 (reference) | (—, —) | ||
| B | 2.17 | (1.50, 3.15) | <0.001 | 2.67 | (1.80, 3.94) | <0.001 |
| C | 2.09 | (1.05, 4.16) | 0.037 | 2.26 | (1.09, 4.65) | 0.028 |
|
| ||||||
| Total tumor diameter∗ | 1.04 | (1.01, 1.07) | 0.009 | 1.04 | (1.01, 1.08) | 0.009 |
|
| ||||||
| mRECIST | 0.034∗∗ | 0.003∗∗ | ||||
| Complete | 1.00 (reference) | (—, —) | 1.00 (reference) | (—, —) | ||
| Partial | 1.15 | (0.77, 1.72) | 0.499 | 1.18 | (0.85, 2.14) | 0.436 |
| Stable | 1.39 | (0.83, 2.33) | 0.209 | 1.28 | (0.55, 2.03) | 0.379 |
| Progressive | 3.21 | (1.42, 7.24) | 0.005 | 4.99 | (1.19, 11.09) | <0.0001 |
∗Sum axial diameter of three largest hepatocellular carcinoma tumors.
∗∗Multiple degree of freedom test to determine if any of the levels within the categorical variables differs from the reference group within that variable.
TACE: transarterial chemoembolization; mRECIST: modified Response Evaluation Criteria In Solid Tumors, p value: probability, and 95% CI: 95% confidence interval.