Table 1.

Correlations between area under the concentration/score curve of changes in cartilage marker, bone turnover markers, and joint swelling score.

	Spearman r
AUC of markers	ΔCTX-I/Cr (AUC)	ΔCTX-II/Cr (AUC)	ΔDPD/Cr (AUC)	ΔNTX/Cr
Joint swelling score (AUC)	0.673∗	0.687∗	0.823∗	0.743∗

Correlation coefficients are shown. ^∗ P < 0.05 (Spearman rank correlation); CTX-I, C-telopeptide fragment of type I collagen; CTX-II, C-telopeptide fragment of type II collagen; DPD, deoxypyridinoline; NTX, N-telopeptide fragment of type I collagen; Cr, creatinine; AUC, area under the concentration/score-versus-time curve.