Table 1.
Description of the Studies Included in the Pooled Analysis of Anthropometric Factors and Thyroid Cancer Risk
| Participants | Thyroid cancer cases | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cohort name | Cohort acronym | Geographic location | Study design | Men | Women | Men | Women | Study period | Years of follow-up, mean (SD) | Age at baseline, mean (SD) | Baseline BMI ≥30 (%) |
| NIH-AARP Diet and Health Study (22) | AARP | U.S. | Cohort | 304,592 | 195,251 | 260 | 327 | 1995–2006 | 9.1 (2.9) | 62.0 (5.4) | 22 |
| Agricultural Health Study (23) | AHS | U.S. | Cohort | 38,383 | 27,458 | 33 | 55 | 1993–2008 | 12.7 (2.5) | 47.2 (12.4) | 22 |
| Breast Cancer Detection Demonstration Project (24) | BCDDP | U.S. | Cohort | — | 38,140 | — | 35 | 1987–1997 | 8.2 (1.7) | 61.7 (8.0) | 13 |
| Cohort of Swedish Men (25) | COSM | Sweden | Cohort | 43,500 | — | 21 | — | 1998–2008 | 9.3 (2.5) | 60.6 (9.7) | 10 |
| Cancer Prevention Study-II (26) | CPSII | U.S. | Cohort | 72,589 | 80,997 | 87 | 129 | 1992–2009 | 12.2 (3.9) | 63.0 (6.4) | 15 |
| Canadian Study of Diet, Lifestyle, and Healtha (27) | CSDLH | Canada | Case-cohort | 4100 | 4268 | 23 | 73 | 1991–2010 | 9.9 (4.9) | 61.2 (13.1) | 10 |
| California Teachers Study (28) | CTS | U.S. | Cohort | — | 104,442 | — | 277 | 1995–2010 | 12.9 (4.0) | 51.9 (13.5) | 14 |
| European Prospective Investigation Into Cancer and Nutrition (29) | EPIC | Europe (multiple sites) | Cohort | 146,430 | 341,073 | 67 | 540 | 1991–2010 | 11.0 (2.8) | 51.3 (9.9) | 14 |
| Iowa Women's Health Study (30) | IWHS | U.S. | Cohort | — | 37,957 | — | 67 | 1986–2005 | 16.4 (5.5) | 62.2 (4.2) | 19 |
| Melbourne Collaborative Cohort Study (31) | MCCS | Australia | Cohort | 15,687 | 22,335 | 12 | 35 | 1990–2009 | 14.9 (4.1) | 55.1 (8.7) | 21 |
| Netherlands Cohort Studyb (32) | NLCS | Netherlands | Case-cohort | 2269 | 2389 | 23 | 52 | 1986–2003 | 14.9 (4.3) | 61.4 (4.2) | 7 |
| New York University Women's Health Study (33) | NYUWHS | U.S. | Cohort | — | 13,306 | — | 48 | 1985–2007 | 18.7 (5.2) | 50.6 (8.7) | 13 |
| Physicians' Health Study (34) | PHS | U.S. | Cohort | 28,350 | — | 51 | — | 1981–2009 | 18.1 (8.4) | 55.3 (9.7) | 6 |
| Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study (35) | PLCO | U.S. | Cohort | 71,068 | 69,990 | 50 | 93 | 1993–2006 | 8.4 (2.8) | 63.1 (5.4) | 24 |
| Sister Study (36) | SISTER | U.S. | Cohort | — | 48,167 | — | 81 | 2003–2012 | 3.7 (1.3) | 55.5 (9.0) | 30 |
| Swedish Mammography Cohort (37) | SMC | Sweden | Cohort | — | 36,375 | — | 16 | 1998–2008 | 9.7 (2.1) | 62.3 (9.2) | 11 |
| Shanghai Men's Health Study (38) | SMHS | China | Cohort | 61,394 | — | 26 | — | 2001–2009 | 5.4 (1.4) | 55.4 (9.7) | 3 |
| Shanghai Women's Health Study (39) | SWHS | China | Cohort | — | 74,861 | — | 163 | 1996–2009 | 10.8 (1.9) | 52.6 (9.1) | 5 |
| U.S. Radiologic Technologists Study (40) | USRT | U.S. | Cohort | 13,317 | 49,395 | 19 | 119 | 1994–2006 | 8.9 (1.5) | 47.9 (8.5) | 16 |
| VITamins And Lifestyle Study (41) | VITAL | U.S. | Cohort | 31,497 | 31,310 | 23 | 69 | 2000–2009 | 7.4 (2.0) | 60.9 (7.3) | 25 |
| Women's Health Study (42) | WHS | U.S. | Cohort | — | 38,946 | — | 101 | 1993–2010 | 14.7 (3.9) | 54.7 (7.0) | 18 |
| Swedish Women's Lifestyle and Health Study (43) | WLH | Sweden | Cohort | — | 44,211 | — | 21 | 1991–2006 | 14.8 (1.7) | 40.2 (5.8) | 6 |
| Overall | 833,176 | 1,260,871 | 695 | 2,301 | 1981–2012 | 10.4 (4.0) | 56.7 (10.3) | 17 | |||
a
Subcohort selected from a full cohort of 34,291 men and 39,618 women.
b
Subcohort selected from a full cohort of 58,279 men and 62,573 women.