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. 2016 Feb 1;26(2):306–318. doi: 10.1089/thy.2015.0319

Table 3.

Sex-Specific Hazard Ratios and Confidence Intervals for Thyroid Cancer and Histological Subtypes According to Anthropometric Factors

  Papillary Follicular Medullary Anaplastic
  No. cases HRa CI No. cases HRa CI No. cases HRa CI No. cases HRa CI
Men
Height (per 5 cm)b,c 396 1.02 0.95–1.10 131 1.09 0.97–1.23 29 1.16 0.90–1.50 19 1.11 0.81–1.51
Baseline BMI (per 5 kg/m2)d 402 1.15 1.02–1.29 132 1.17 0.95–1.44 31 1.25g 0.80–1.93 19 0.85h 0.45–1.63
Waist circumference (per 5 cm)e 198 1.04 0.97–1.11 62 1.02 0.90–1.15 12 0.99 0.74–1.32 7 0.80 0.53–1.20
Young-adult BMI (per 5 kg/m2)d 238 1.27 1.05–1.54 81 0.90 0.61–1.31 12 1.17 0.47–2.94 12 1.33 0.56–3.17
Adulthood BMI gain (per 5 kg/m2)f 238 1.24 1.05–1.46 81 1.24 0.92–1.66 12 0.97 0.43–2.22 12 1.12 0.51–2.46
Women
Height (per 5 cm)b,c 1663 1.08 1.04–1.12 248 1.15 1.04–1.26 61 0.95 0.78–1.16 23 1.21 0.89–1.66
Baseline BMI (per 5 kg/m2)d 1676 1.01 0.96–1.06 249 1.13 1.00–1.28 61 0.65g 0.47–0.91 23 1.66h 1.23–2.23
Waist circumference (per 5 cm)e 802 1.01 0.98–1.04 139 1.07 1.00–1.15 35 0.84 0.71–0.99 9 1.22 0.96–1.56
Young-adult BMI (per 5 kg/m2)d 481 1.10 0.95–1.27 100 1.15 0.84–1.59 16 0.58 0.20–1.70 7 1.43 0.51–4.04
Adulthood BMI gain (per 5 kg/m2)f 481 1.03 0.94–1.14 100 1.01 0.81–1.25 16 0.41 0.19–0.86 7 2.13 1.20–3.78
Totali
Height (per 5 cm)b,c 2059 1.07 1.03–1.10 379 1.13 1.04–1.21 90 1.02 0.87–1.20 42 1.17 0.94–1.46
Baseline BMI (per 5 kg/m2)d 2078 1.03 0.98–1.08 381 1.14 1.02–1.26 92 0.80 0.62–1.03 42 1.43 1.09–1.89
Waist circumference (per 5 cm)e 1000 1.01 0.98–1.04 201 1.06 1.00–1.13 47 0.87 0.76–1.01 16 1.07 0.86–1.32
Young-adult BMI (per 5 kg/m2)d 719 1.16 1.03–1.30 181 1.03 0.80–1.32 28 0.86 0.44–1.69 19 1.38 0.71–2.67
Adulthood BMI gain (per 5 kg/m2)f 719 1.08 0.99–1.17 181 1.09 0.92–1.30 28 0.59 0.34–1.00 19 1.60 1.01–2.54

Statistically significant values (p < 0.05) are shown in bold.

a

Adjusted for age (used as time metric), alcohol intake (0–9, 10–19, or ≥20 g of ethanol per day), physical activity level (cohort-specific tertiles), race/ethnicity (white, black, Asian, other), marital status (married/living together, divorced/separated, widowed, single/never married), education (high school or less, some college/post-high school training, college graduate), and smoking status (never, former, current), and stratified by cohort.

b

Additionally adjusted for baseline BMI (per 5 kg/m2).

c

Restricted to height values between 122 and 244 cm.

d

Restricted to BMI values between 15.0 and 59.9 kg/m2.

e

Restricted to waist circumference values between 52 and 189 cm.

f

Additionally adjusted for young-adult BMI (per 5 kg/m2).

g

p = 0.02.

h

p = 0.03.

i

Additionally adjusted for sex.