Overview |
CD is a lifelong condition characterized by inflammation of the gastrointestinal tract |
UC is a lifelong condition characterized by chronic inflammation of the colon |
CD has a relapsing and remitting course |
UC has a relapsing and remitting course |
The causes of CD are unknown but are believed to be a mixture of genetic and environmental factors |
The causes of UC are unknown but are believed to be a mixture of genetic and environmental factors |
The onset of CD is most common in the second and third decades of life |
UC primarily presents in late adolescence and early adulthood |
Diagnosis |
CD is diagnosed by clinical evaluation and a combination of endoscopic, histological, radiological, and/or biochemical investigations |
UC is diagnosed by clinical evaluation, proctosigmoidoscopy or endoscopy, biopsy, and negative stool examination for infective causes |
Chronic diarrhea is the most common presenting symptom of CD |
Visible blood in the stools is the primary presenting symptom in UC |
Common symptoms of CD include chronic diarrhea, nocturnal diarrhea, abdominal pain, weight loss, fever, rectal bleeding |
Common symptoms of UC include bloody diarrhea, rectal bleeding, and/or rectal urgency |
Management goals |
Goals of management in CD are the treatment of acute disease or induction of clinical remission, followed by maintenance of remission |
Goals of treatment in UC are remission of symptoms, improved quality of life, reduction in long-term medication needs, and reduction of cancer risk |
Treatment options |
Initiation of therapy should be performed by a specialist gastroenterologist |
GPs are important in monitoring long-term treatment plan |
Therapy is divided into two categories: (1) acute therapy for flares to induce remission and (2) maintenance therapy in order to help maintain remission |
Treatment for IBD may include pharmacological therapy and surgical therapy |
Surgical therapy involves removal of a section of bowel, which may result in the patient living with a stoma for life |
Use of complementary and alternative medicine is generally safe, but efficacy is not validated |