Table 4. Association results of 3 tested SNPs with obesity-related traits in the replication sample, GIANT and DIAGRAM Consortiums.

			BMI				Fat Mass				WHRadjBMI				GIANTb
SNP	A1/A2a	MAF	β	P	βmeta	Pmeta	β	P	βmeta	Pmeta	β	P	βmeta	Pmeta	WHRadjBMI	HIPadjBMI	DIAGRAMc
rs167428	C/T	0.110	−0.385	0.053	−0.374	2.48 × 10−3	−0.684	0.044	−0.888	3.46 × 10−5	−3.34 × 10−3	0.402	−3.90 × 10−3	0.111	0.44	0.15	0.29
rs308442	A/T	0.196	−0.083	0.595	−0.156	0.111	−0.099	0.710	−0.517	2.38 × 10−3	−2.57 × 10−3	0.414	−1.90 × 10−3	0.339	0.19	6.8 × 10−2	0.18
rs1048201	T/C	0.442	−0.261	0.040	0.005	0.951	−0.481	0.044	0.139	0.314	−1.56 × 10−3	0.533	−1.00 × 10−3	0.529	0.037	3.8 × 10−4	0.01

MAF, minor allele frequency. β is calculated with respect to the minor allele. Meta-analysis was performed with effect size estimates weighted by the inverse of the corresponding standard errors (βmeta and Pmeta).

^aA1 represents the minor allele.

^bWHRadjBMI and HIPadjBMI association P values are from the GIANT Consortium of 210,088 European individuals.

^cP values are from the DIAGRAM Consortium of 12,171 T2D cases and 56,862 controls of European descent.