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. 2016 Feb 16;6:21231. doi: 10.1038/srep21231

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Highly conserved residues are indicated with black backgrounds and similar residues are shaded. The cupin superfamily motifs are indicated in the top line. Dashes indicate gaps. Asterisks show highly conserved cysteine and tyrosine residues formation of cross-linked cofactor of CDO. From top to bottom, the sequences are from Paralichthys olivaceus (KP739882), Oncorhynchus mykiss (KP739883), Danio rerio (Q6NWZ9), Mus musculus (NP_149026), Rattus norvegicus (AAH70509), Homo sapiens (AAH24241), and Xenopus laevis (NP_001083506)