Skip to main content
. 2016 Feb 16;6:21262. doi: 10.1038/srep21262

Figure 4. Accumulation of fibrillar interstitial collagen induced by NTS was arrested in mice treated with DDR1 antisense.

Figure 4

Upper: Representative views (scale bar = 50μm) of Sirius Red coloration on renal sections at day 15 in NTS + Scr4 (A) and NTS + As4 (B) mice showing accumulation of interstitial fibrillar collagen. Middle: Quantification of fibrillar collagen at day 15 in As4 and As8 protocols. n = 10–15. ***p < 0.001 vs Control; ###p < 0.001 vs NTS + Scrambled. Lower: mRNA expressions of collagen I α2 and collagen III a1 in mice treated either with As or with Scr from day 4 or 8 and sacrificed at day 15. n = 4–10; **p < 0.01, and ***p < 0.001 vs Control; ##p < 0.01, and ###p < 0.001 vs NTS + Scrambled.