Table 3. The effect of eGFR or albuminuria on regional cortical thickness.
| Overall | Frontal lobe | Temporal lobe | Parietal lobe | Occipital lobe | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| B (SE) | pvalue | B (SE) | pvalue | B (SE) | pvalue | B (SE) | pvalue | B (SE) | pvalue | |
| eGFR (ml/min/1.73m2) | ||||||||||
| ≥105 | −0.005 (0.012) | 0.678 | −0.006 (0.013) | 0.659 | −0.023 (0.018) | 0.770 | 0.001 (0.015) | 0.953 | −0.003 (0.014) | 0.802 |
| 90–104 | references | |||||||||
| 75–89 | 0.008 (0.007) | 0.278 | 0.010 (0.008) | 0.174 | 0.011 (0.011) | 0.758 | 0.001 (0.009) | 0.879 | 0.013 (0.008) | 0.125 |
| 60–74 | −0.002 (0.008) | 0.800 | 0.001 (0.009) | 0.939 | 0.004 (0.013) | 0.305 | −0.011 (0.011) | 0.303 | 0.010 (0.010) | 0.289 |
| <60 | −0.013 (0.014) | 0.341 | −0.009 (0.015) | 0.543 | 0.006 (0.021) | 0.203 | −0.024 (0.018) | 0.167 | −0.008 (0.016) | 0.600 |
| UACR (mg/g) | ||||||||||
| Normal | references | |||||||||
| Elevated | −0.023 (0.009) | 0.015 | −0.027 (0.010) | 0.008 | −0.024 (0.015) | 0.100 | −0.010 (0.012) | 0.418 | −0.031 (0.011) | 0.005 |
eGFR, estimated glomerular filtration rate; UACR, urinary albumine to creatinine ratio; elevated UACR if the value was ≥30 mg/g; SE, standard error. Linear regression analysis adjusted for age, sex, history of hypertension, diabetes mellitus, hyperlipidemia, ischemic heart disease, and stroke, fasting glucose, systolic blood pressure, diastolic blood pressure, total cholesterol level, body mass index, status of current smoking and alcohol drinking, education level and intracranial volume, GFR groups or UACR.