Table 1. Parasitological treatment responses of Aotus monkeys infected with a Plasmodium falciparum C2A clone.
| Group | ID | Aotus | Weight g. | Parasitemia | Day of peak | Group | Regimen mg/Kg | Route | Treatment | Day of treatment | Day rescue | Results primary |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sex | Peak 103 × μL | Duration days | ||||||||||
| 1 | 26058 | 2 | 829 | 104.60 | 11 | MQ | 40 | p.o. | 1 | 11 | 14 | Failed |
| 1 | 26033 | 1 | 758 | 272.74 | 9 | MQ | 40 | p.o. | 1 | 9 | 5 | Failed |
| 2 | 22028 | 2 | 764 | 449.73 | 9 | AS | 33 | p.o. | 3 | 9 | 10 | Failed |
| 2 | 26045 | 1 | 789 | 110.58 | 11 | AS | 33 | p.o. | 3 | 11 | 8 | Failed |
| 3 | 26063 | 1 | 782 | 177.84 | 9 | AS + MQ | 33 + 40 | p.o. | 3 + 1 | 9 | 16 | Failed |
| 3 | 26025 | 2 | 785 | 106.02 | 10 | AS + MQ | 33 + 40 | p.o. | 3 + 1 | 10 | None | Failed |
| 4 | 23042 λ | 1 | 724 | 0.340 | 16 | AS + MQ | 33 + 40 | p.o. | 3 + 1 | 16 | None | Cured |
Male = 1; Female = 2.
MQ = mefloquine; AS = artesunate.
λ = spleen intact.
p.o. = per os.