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(A,B) Mouse embryo fibroblast cells were infected with viruses expressing shCon or shFST. The FST mRNA level was detected by qPCR (A) and the FST protein level was detected by immunoblotting (B–D) Mouse lung infected with shCon or shFST was instilled with PBS or 100 μg of SiO2 NPs for 1 day. (C) Cell apoptosis was detected by TUNEL assay. (D) TUNEL positive cells were quantified. The values are the mean ± SD. **P < 0.01.
