Table 2.

Measurements of left ventricular (LV) function in rats by M-mode echocardiography from the parasternal short axis at the mid papillary muscle level, and colourful-Doppler across the mitral valve from the apical four chamber views

	6 Weeks		12 Weeks		P-value
	Control Rats	Model Rats	Control Rats	Model Rats	P1	P2	P3	P4
	(n = 8)	(n = 8)	(n = 8)	(n = 7)
AWD(mm)	1.82 ± 0.20	1.82 ± 0.17	1.74 ± 0.22	1.74 ± 0.25	0.9445	0.4912	0.7806	0.3278
AWS (mm)	2.86 ± 0.39	2.89 ± 0.32	2.59 ± 0.38	2.43 ± 0.19	0.9521	0.1701	0.2972	0.0091
PWD (mm)	2.15 ± 0.22	2.01 ± 0.33	1.87 ± 0.19	1.70 ± 0.23	0.3284	0.1142	0.0230*	0.0652
EDD (mm)	7.44 ± 0.39	7.69 ± 0.99	7.47 ± 0.57	7.58 ± 0.57	0.5227	0.7959	0.6183	0.6498
EF (%)	72.61 ± 6.38	68.19 ± 8.64	66.37 ± 7.06	59.34 ± 5.27	0.2641	0.0629	0.0724	0.0651
FS (%)	43.33 ± 5.46	39.82 ± 7.03	38.22 ± 5.74	32.69 ± 3.65	0.2842	0.0613	0.0748	0.0330*
EDV (ml)	293.78 ± 32.90	321.15 ± 93.93	308.12 ± 51.21	299.13 ± 58.17	0.4496	0.8122	0.5800	0.6012
ESV (ml)	80.28 ± 19.33	106.38 ± 48.40	105.11 ± 31.42	124.43 ± 35.19	0.1784	0.2979	0.0782	0.4485
E/A Ratio	1.54 ± 0.17	1.83 ± 0.51	1.68 ± 0.26	1.56 ± 0.18	0.1477	0.3586	0.2440	0.2109
MVDT(ms)	14.17 ± 5.80	17.45 ± 8.91	16.03 ± 2.56	16.77 ± 2.96	0.3969	0.6258	0.4473	0.8504

Data are presented as mean ± SD. Abbreviations AWD anterior wall in diastole, AWS anterior wall in systole, PWD posterior wall in diastole, EDD end-diastolic diameter, EF ejection fraction, FS fractional shortening, EDV end-diastolic volume, ESV end-systolic volume, E/A Ratio ratio of the early (E) to late (A) ventricular filling velocities, MVDT mitral valve deceleration time

P1 and P2, Model group compared to control group; P3 and P4, 12-week compared to 6-week group, *P<0.05