Table 2.
Distribution of JAZF1/SUZ12 fusion transcript in different histological subtypes of ESTs
| ESN, total (+) | ESS, total (+) | UES, total (+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Ref. | Classic | SM | Mixed | Classic | SM | EP | FM | SC | Mixed | UES-U | UES-P |
| [3] | 3a (3) | 5a (5) | |||||||||
| [6] | 1 (1) | 1 (1) | - | 3 (3) | 2 (0) | 2 (0) | 2 (0) | - | - | - | - |
| [7] | - | - | - | 16 (14) | - | - | 1 (1) | 1 (0) | 1 (1) | - | 2 (0) |
| [8] | 2 (2) | 2 (2) | 16 (8) | ||||||||
| [9], [12] | 6 (4) | - | - | 11 (5) | - | - | - | 1 (0) | - | 3 (1) | 3 (0) |
| [10] | 5 (2) | - | - | 1 (1) | - | - | - | - | - | - | - |
| [35] | 2 (1) | - | 1 (0) | 5 (1) | 1 (0) | - | - | 4 (0) | 3 (0) | 3 (0) | 4 (0) |
| [44] | - | - | - | 16a (7) | - | - | - | - | - | 6a (0) | - |
| Total Nr. | 19 (13) | 3 (3) | 1 (0) | 73 (44) | 3 (0) | 2 (0) | 3 (1) | 6 (0) | 4 (1) | 12 (1) | 9 (0) |
| + / total (n = 135) | 9.6 % | 2.2 % | - | 32.6 % | - | - | 0.7 % | - | 0.7 % | 0.7 % | - |
| + / type | 69.6 % | 50.5 % | 4.8 | ||||||||
| + / subtype | 68 % | 100 % | - | 60 % | - | - | 33 % | - | 25 % | 8 % | - |
Abbreviations: Ref references, ESN endometrial stromal nodule, LG-ESS low-grade endometrial stromal sarcoma, UES undifferentiated endometrial sarcoma; classic, with classic histology, SM with smooth muscle differentiation, EP with epithelioid features, FM with fibromyxoid features, SC with sex cord-like differentiation, U with nuclear uniformity, P with nuclear pleomorphism
a,morphologic subtype was not precisely described in original paper; +, positive for JAZF1/SUZ12 fusion transcript; total, number of samples suitable for analyses (cases described in original paper as “non informative” or “not analyzed” were excluded from calculations)