Table 3.
The changes of the inflammatory cell populations in peripheral blood after chemotherapy (n = 6, %, mean ± SEM)
| Cell population | Peripheral blood | ||||
|---|---|---|---|---|---|
| Control | Chemo. | Chemo. + ASP | Chemo. + Lip | Chemo. + ASP + LIP | |
| Th | 13.46 ± 3.33 | 12.01 ± 3.48 | 13.12 ± 2.16 | 12.98 ± 2.01 | 12.01 ± 1.30 |
| CTL | 10.44 ± 2.65 | 9.22 ± 2.65 | 8.11 ± 2.05 | 10.11 ± 3.44 | 9.40 ± 1.75 |
| B cells | 27.52 ± 5.01 | 26.04 ± 5.12 | 31.01 ± 5.01 | 22.24 ± 4.01 | 24.88 ± 6.27 |
| Granulocyte | 45.55 ± 7.71 | 32.33 ± 5.75 | 32.55 ± 4.66 | 35.46 ± 4.44 | 38.22 ± 4.77 |
| Mφ | 13.12 ± 3.44 | 17.11 ± 2.52 | 9.11 ± 2.05 | 13.11 ± 4.08 | 14.01 ± 3.58 |
| DC | 7.34 ± 2.06 | 15.42 ± 2.34* | 17.77 ± 4.37* | 15.88 ± 1.34* | 18.24 ± 2.07* |
| NK | 6.56 ± 2.18 | 7.50 ± 2.04 | 5.44 ± 1.25 | 6.80 ± 1.22 | 7.70 ± 1.22 |
| NKT | 2.29 ± 1.40 | 3.01 ± 1.26 | 3.01 ± 0.67 | 3.20 ± 0.67 | 3.80 ± 1.04 |
| MDSC | 23.21 ± 4.29 | 14.70 ± 3.14* | 7.20 ± 2.45** # | 16.01 ± 3.24*& | 9.28 ± 1.24** # |
| M1 | 7.87 ± 2.88 | 10.85 ± 1.45 | 8.58 ± 3.44 | 9.05 ± 2.75 | 11.57 ± 2.76 |
| M2 | 2.91 ± 1.58 | 7.11 ± 1.54* | 3.01 ± 1.05# | 11.01 ± 2.04** # | 5.22 ± 1.77 |
Th helper T cells, CTL cytotoxic T lymphocyte, Mφ monocyte & macrophage, DC dendritic cells, NK natural killer cells, NKT natural killer T cells, MDSC myeloid derived suppressor cells, M1 M1-polarized tumor associated macrophages, M2 M2-polarized tumor assocaited macrophages. Compared with Control group, * P < 0.05, ** P < 0.01; Compared with Chemo.group, # P < 0.05, ## P < 0.01; Compared with Chemo. + ASP group, & P < 0.05,&& P < 0.01; ANOVA analysis, SNK-q test