Fig. 7.

Swollen afferent type I terminals and reduced GLAST expression in young adult Pit1^dw mice. (a and b) Representative TEM images from the mid-turn of Pit1^dw and WT cochleas at P42. IHC and afferent boutons (aff) are indicated. Scale bar: 2 lm. (c and d) Projections of confocal sections obtained from the mid-turn of cochlear whole mounts co-stained with anti-GLAST (red) and anti-myosin VIIa (green) antibodies in WT and Pit1^dw mice at P14. (e and f) GLAST expression (red) alone in WT and Pit1^dw mice at P14 before TH treatment. (g and h) GLAST expression (red) at P14 in saline-treated WT mice and in TH-treated Pit1^dw mice from P3 to P8. Scale bar: 10 lm.