Table 1.
The basic information about the included studies
| References | Definition of tumor-cell positivity | Detection method | Target gene/antigen | Follow-up (months) | Outcomes reported | stage | Multivariate analysis | |
|---|---|---|---|---|---|---|---|---|
| Median | Range | |||||||
| Chun-Dong Gu | LNMM | IHC | CK(AbAE1/A) | 44 | 4 –60 | OS | I | Yes |
| Kazuhito Dobashi | LNMM | IHC | CK(AbAE1/A) | 13.6 | 1-60 | OS | pN0 | Yes |
| B. Passlick | LNMM | IHC | CK | NR | NR | OS | pN0 | Yes |
| Jakob R. Izbicki, | LNMM | IHC/FCM | Ber-Ep-4 | NR | 3-40 | DFS | pN0 | Yes |
| By Toshihiro Osaki | LNMM | IHC | CK(AbAE1/A) | 35.8 | 0.1-90.6 | OS | I | Yes |
| Kosei Yasumoto | LNMM | IHC | CK2 | 48.2 | 1-64 | OS/DFS | I | Yes |
| Valerie W. Rusch | LNMM | IHC | CK(AE-1) | NR | 0-60 | OS/DFS | pN0 | Yes |
| Wang Zhou | LNMM | RT-PCR | MUC1 | NR | 0-36 | OS | pN0 | Yes |
Abbreviations: LMMM lymph node micrometastases, IHC immunohistochemistry, CK cytokeratin, DFS disease- free survival, OS overall survival, NR not reported, RT-PCR Reverse transcription-polymerase chain reaction. MUC1, polymorphic epithelial mucin 1