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. 2016 Feb 16;14:53. doi: 10.1186/s12967-016-0809-9

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© Liu et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Biological effect of long term high-protein diet in rats. a Urinary urea concentration. b Urinary osmolality. c Blood urea. d Water consumption. e Urine output. f Representative magnification image of the bladder in control group. g High magnification image of box in f. h Representative magnification image of the bladder in HPD group. i High magnification image of box in h. Asterisk Interstitial congestion, inflammatory infiltrates, nucleus swelling and malformed. Arrows Endothelial cells thinned, desquamation, cytoplasm vacuolization