Table 5.
Factors associated with initial route of MTX Administration in idiopathic uveitis
| Multivariable Logistic Regression | ||||||
|---|---|---|---|---|---|---|
| Variable | Oral MTX | SQ MTX | Univariate P value | Odds Ratio | 95 % CI | P value |
| N = 31 | N = 36 | |||||
| Age at onset, yrs | 0.06 | 0.61 | ||||
| Median (IQR) | 9.4 (5.7-11.8) | 7.1 (5.0-9.3) | ||||
| Gender | 1.00 | 0.73 | ||||
| Female | 13 (42 %) | 15 (42 %) | ||||
| Male | 18 (58 %) | 21 (58 %) | ||||
| Ethnicity | 1.00 | 0.72 | ||||
| Hispanic | 2 (6 %) | 2 (6 %) | ||||
| Non-Hispanic | 29 (94 %) | 34 (94 %) | ||||
| Race | 0.046* | 12.7 | 1.5-106.8 | 0.003* | ||
| Caucasian | 27 (87 %) | 22 (65 %) | ||||
| Non-Caucasian | 4 (13 %) | 12 (35 %) | ||||
| Uveitis type | 0.65 | 0.51 | ||||
| Anterior | 19 (61 %) | 26 (72 %) | ||||
| Pan | 4 (13 %) | 5 (14 %) | ||||
| Intermediate | 7 (23 %) | 4 (11 %) | ||||
| Posterior | 1 (3 %) | 1 (3 %) | ||||
| ANA status | 1.00 | 0.95 | ||||
| Positive | 11 (44 %) | 15 (44 %) | ||||
| Negative | 14 (56 %) | 19 (56 %) | ||||
| Complications** | 25 (81 %) | 28 (80 %) | 1.00 | 0.73 | ||
| Cataracts | 15 (48 %) | 16 (44 %) | 0.81 | 0.94 | ||
Data in this table include subject characteristics associated with the route of methotrexate administration initially prescribed
IQR interquartile range, SQ subcutaneous, CI confidence interval, ANA antinuclear antibody
*Statistically significant, **Presence of at least one ocular complication