Table 6.
Factors associated with biologic agent use in idiopathic uveitis
| Multivariable Logistic Regression | ||||||
|---|---|---|---|---|---|---|
| Variable | Biologics | No Biologics | Univariate P value | Odds Ratio | 95 % CI | P value |
| N = 49 | N = 43 | |||||
| Age at onset, yrs | 0.35 | 0.90 | ||||
| Median (IQR) | 7.7 (5.1-10.2) | 8.9 (6.8-11.4) | ||||
| Gender | 0.21 | 0.07 | ||||
| Female | 24 (49 %) | 27 (63 %) | ||||
| Male | 25 (51 %) | 16 (37 %) | ||||
| Ethnicity | 0.54 | 0.92 | ||||
| Hispanic | 5 (10 %) | 7 (16 %) | ||||
| Non-Hispanic | 44 (90 %) | 36 (84 %) | ||||
| Race | 0.20 | 0.87 | ||||
| Caucasian | 35 (73 %) | 36 (86 %) | ||||
| Non-Caucasian | 13 (27 %) | 6 (14 %) | ||||
| Uveitis type | 0.44 | 0.82 | ||||
| Anterior | 27 (55 %) | 30 (70 %) | ||||
| Pan | 13 (27 %) | 6 (14 %) | ||||
| Intermediate | 7 (14 %) | 5 (12 %) | ||||
| Posterior | 2 (4 %) | 2 (5 %) | ||||
| ANA status | 0.07*** | |||||
| Positive | 20 (49 %) | 10 (29 %) | 3.0 | 1.0-8.6 | 0.04* | |
| Negative | 21 (51 %) | 25 (71 %) | Reference | |||
| Any complication | 39 (81 %) | 32 (74 %) | 0.46 | 0.16 | ||
| Cataracts | 26 (53 %) | 9 (21 %) | 0.002* | 5.6 | 1.8-17.2 | 0.001* |
IQR interquartile range, CI confidence interval
*Statistically significant, ***Trend