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. 2016 Feb 10;270(1):165–177. doi: 10.1111/imr.12386

Figure 6.

Figure 6

Hapten‐binding bsAbs for targeted payload delivery. (A) Dig‐coupled flourophore complexed with bsAbs that target tumor‐associated cell surface antigens (e.g. HER2) accumulate the payload at the tumors. (B) Hapten‐coupled nucleic acids (Dig‐payload) can be coupled to bsAbs and delivered to and into target cells where payload (red) and targeting vehicles (green) separate in vesicular compartments.