Table 3.

Difference in Biomarkers of Genotoxicity and Epigenotoxicity Between Welders and Controls

		Unadjusted			Adjusteda
		Effect	95% CI	P	Effect	95% CI	P
8‐oxodGb	Occupation groups	1.4	−0.12–2.9	0.070	1.2	−0.48–2.8	0.17
Telomere lengthb	Occupation groups	−0.048	−0.10–0.0075	0.090	−0.053	−0.11–0.0071	0.083
DNA methylation indexc	Occupation groups	1.3	0.76–2.1	0.37	1.2	0.69–2.09	0.52
HOXA9 methylationd	Occupation groups	4.1	0.88–19	0.073	3.7	0.73–19	0.11
SHOX2 methylationd	Occupation groups	0.80	0.47–1.4	0.42	0.84	0.46–1.5	0.56
CDKN2A methylationd	Occupation groups	1.3	0.75–2.2	0.35	1.1	0.62–2.0	0.71
MGMT methylationd	Occupation groups	1.0	0.49–2.1	0.99	1.3	0.58–2.7	0.57
APC methylationd	Occupation groups	14	1.7–109	0.014	8.9	0.98–81	0.052

^aAdjustment included age, BMI, previous smoking, passive smoking, current residence, and wood burning stove/boiler at home.

^bGeneral linear model with effect as beta estimate.

^cOrdinal regression model with effect as odds ratio.

^dLogistic regression model with effect as odds ratio.