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. Author manuscript; available in PMC: 2016 Feb 16.
Published in final edited form as: Eur J Med Chem. 2015 Dec 13;108:577–585. doi: 10.1016/j.ejmech.2015.12.014

Fig. 6.

Fig. 6

Flow cytometry analysis (cell associated fluorescence vs cell count) of MCF7σ1 and MCF7wt, exposed to 5 or 6 and treated with 10 (10 µM) to mask σ2 receptors. A) Displacement of 5 (100 nM, yellow curve) with increasing concentrations of (+)-pentazocine: black curve: control; orange curve: 1 nM (+)-pentazocine; red curve: 10 nM (+)-pentazocine; green curve: 100 nM (+)-pentazocine; blue curve: 1 µM (+)-pentazocine; violet curve: 10 µM (+)-pentazocine. B) Displacement of 6 (100 nM, yellow curve) with increasing concentrations of (+)-pentazocine: black curve: control; orange curve: 1 nM (+)-pentazocine; red curve: 10 nM (+)-pentazocine; green curve: 100 nM (+)-pentazocine; blue curve: 1 µM (+)-pentazocine; violet curve: 10 µM (+)-pentazocine.