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. Author manuscript; available in PMC: 2017 Feb 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2016 Feb;9(2):e003180. doi: 10.1161/CIRCEP.115.003180

Table 1.

Genetically modified mice

MICE	MUTATIONS	NOTES	CONTROL	SOURCE
Pln ^−/−	Pln ^−/−	Background for all PLN mutant mice	WT^, WT-Pln*	MMRRC
S16A	PLN S16A	TG replacement of S16A in the Pln^−/− background	S16A(−), WT-Pln	MMRRC
T17A	PLN T17A	TG replacement of T17A in the Pln^−/− background	T17A(−), WT-Pln	MMRRC
S16A(−)	Pln ^−/−	Littermates of S16A lacking TG S16A		MMRRC
T17A(−)	Pln ^−/−	Littermates of T17A lacking TG T17A		MMRRC
WT-Pln	WT-PLN	TG replacement of WT PLN in the Pln^−/− background		MMRRC
N27A	PLN N27A	TG replacement of N27A PLN in the Pln^−/− background	WT^, N27A(−), WT-Pln*	MMRRC
N27A(−)	Pln ^−/−		WT-Pln	MMRRC
S2808A	S2808A		S2808A(−)	HV lab
S2814A	S2814A		WT^*, S2814A(−)	XW lab
S2808A(−)		Littermates of S2808A with WT RyR2		HV lab
S2814A(−)		Littermates of S2814A with WT RyR2		XW lab
AC3-I X PLN^−/−	AC3-I & PLN^−/−		AC3-I(−) & PLN^−/−	MEA lab
AC3-C X PLN^−/−	AC3-C & PLN^−/−		AC3-C(−) & PLN^−/−	MEA lab
AC3-I(−)		littermate control lacking tg AC3-I		MEA lab
AC3-C(−)		littermate control lacking tg AC3-C		MEA lab

^*

WT mice in C57 background