Table 2.
Specific indirect and direct effects of childhood disadvantage on midlife cortisol levels: all measures standardized.
| Mediator | AUC Cortisol β (95% CI lower; 95% CI upper) | Wake to bed slope β (95% CI lower; 95% CI upper) | Cortisol Awakening Response (CAR) β (95% CI lower; 95% CI upper) |
|---|---|---|---|
| Age 20 Cognitive ability (M1: a1b1) | 0.02 (0.002; 0.04) | .02 (0.01; 0.04) | .01 (−0.005; 0.03) |
| Midlife SES (M2: a b) | 0.013 (0.002; 0.027) | .007 (−.001; 0.02) | .007 (−.002; 0.02) |
| Midlife SES adjusted for Age 20 Cognitive Ability (a1eb2) | 0.006 (0.001; 0.012) | .003 (−0.001; 0.008) | .003 (−0.001; 0.009) |
| Total indirect effect | 0.04 (0.02; 0.06) | .03 (0.01; 0.05) | .02 (0.002; 0.05) |
| Direct effect of childhood disadvantage (c′) | 0.08 (0.01; 0.14) | −.006 (−0.07; 0.05) | .01(−.06; 0.09) |
| Total effect of childhood disadvantage (c) | 0.12 (0.05; 0.18) | .02 (−0.04; 0.08) | .04 (−.03; 0.10) |
Notes: Confidence intervals based on 1000 bootstrap samples; coefficients are standardized values (x = 0; SD = 1). CI = confidence interval; significant values are bolded. M1 = specific indirect effect of childhood risk through age 20 cognitive ability; M2 = specific indirect effect of childhood risk through midlife socioeconomic status (SES).