Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The cGAS-STING Dependent DNA Sensing Pathway
A detailed overview of the cGAS-STING DNA sensing pathway is depicted. Both positive and negative regulators of STING are shown. Black arrows indicate pathways that lead to activation of STING and induction of the type I IFN response. White arrows indicate pathways that negatively regulate STING. Protein ubiquitination is depicted as K48 or K63 linkages, and protein phosphorylation is depicted as P.
