Table 3.

Rotavirus Immunoglobulin A Seroconversion by Interval Between Administration of Monovalent Rotavirus Vaccine and Oral Poliovirus Vaccine^a

Population and Doses Compared	Rotavirus IgA Seroconversion	Infants, No.	Interval Between Administration of RV1 and OPV, Median (IQR) d	P Valueb
Total (n = 409)
1st doses of OPV and RV1	No	179	1 (0–7)	<.001
	Yes	230	5 (0–11)
2nd doses of OPV and RV1	No	179	11 (4–18)	.04
	Yes	230	14 (7–19)
Staggered administration only (n = 235)
1st doses of OPV and RV1	No	86	7 (5–9)	.06
	Yes	149	8 (5–13)
2nd doses of OPV and RV1	No	86	12 (9–18)	.11
	Yes	149	14 (9–20)

Abbreviations: IgA, immunoglobulin A; IQR, interquartile range (25%–75%); OPV, oral poliovirus vaccine; RV1, monovalent rotavirus vaccine.

^aRotavirus seroconversion and its relationship with the interval between administration of RV1 and OPV were assessed in the total population and among infants who received the vaccines staggered ≥1 day apart for doses 1 and 2 (regardless of which vaccine was administered first).

^bBased on Mann–Whitney tests.