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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: J Pharm Sci. 2016 Jan 6;105(2):406–416. doi: 10.1016/j.xphs.2015.10.018

Table 4.

ET-CO-RMs structures and CO release properties

Compounds Chemical structures Solubility Half-life Enzyme trigger Eq. of CO released
1 graphic file with name nihms-737265-t0007.jpg DMSO RAMEB 128 min Esterase 2.4
2 graphic file with name nihms-737265-t0008.jpg DMSO RAMEB 12 min Esterase 2.4
4 graphic file with name nihms-737265-t0009.jpg DMSO ~45 min Esterase 2.4
5 graphic file with name nihms-737265-t0010.jpg H2O 135 min Phosphatase 2.78
6 graphic file with name nihms-737265-t0011.jpg DMSO >100 h Penicillin G amidase (PGA) <0.25
7 graphic file with name nihms-737265-t0012.jpg DMSO ~30 h PGA 1.5