Table 3. Ancestral haplotypes inferred by Phase software.
| Study group | Mutated chromosomes | Mutated chromosomes with ancestral haplotype | rs1700490:C>T | rs729459:C>T | rs11249784:A>G | rs4507507:C>G | VARIANT | rs7449323:C>G | rs10036388:G>T | rs1110162:A>G | rs4976788:C>T | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Physical distance (Mb) | 1.02 | 0.39 | 0.04 | 0.01 | 0.00 | 0.08 | 0.14 | 0.34 | 0.54 | |||
| c.[301_302delAG] | Europea | 279 | 213 | C/T | C/T | A | C | delAG | C | G | A/G | C/T |
| Portugal and Spain | 22 | 15 | T | T | A | G | delAG | C | G | A/G | C/T | |
| Latin America 1b | 36 | 33 | C/T | T | A | G | delAG | C | G | A/G | C/T | |
| Latin America 2c | 24 | 23 | C/T | C/T | A | C | delAG | C | G | A | T | |
| North Americad | 17 | 16 | C/T | C/T | A | C | delAG | C | G | A/G | C/T | |
| c.[150delA] | Altogethere | 100 | 84 | C/T | C/T | A/G | C | delA | G | G | A | C/T |
a
Excluding patients from Iberian Peninsula (Portugal and Spain).
b
Argentina, Dominican Republic and partly Brazil.
c
Jamaica, Panama and partly Brazil.
d
USA and Canada.
e
Belarus, Croatia, Czech Republic, Germany, Lithuania, Panama, Poland, Russia, Slovakia, Slovenia, USA.
Ancestral haplotypes are indicated by bold. Reference sequence: NM_0006261.4.