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. 2016 Feb 16;110(3):163–172. doi: 10.1093/trstmh/trv107

Figure 2.

Figure 2.

WHO recommended groupings of multidrug-resistant TB (MDR-TB) drugs.

aThere are high rates of streptomycin resistance in MDR-TB strains; it is not considered a second line anti-TB injectable agent. bGatifloxacin may have side-effects including dysglycaemia. It has been removed from the market in several countries. Early generation fluoroquinolones do not high adequate activity against MDR-TB. cTerizidone may also be listed as Group 4 anti-TB drug. It has limited programmatic and efficacy data compared to the others. dOther Group 5 drugs, with variable in vitro and animal data to support use include amoxicillin/calvulanate, imipenem/cilastatin, meropenem, thioacetazone and clarithromycin.