Table III.
Karyotyping results and associations with LDA among losses in the EAGeR trial.
| Karyotype results | Total | Abnormal karyotype | Normal | Unable to determine | Not tested |
|---|---|---|---|---|---|
| N (N LDA/N Placebo) | 1228 (615/613) | 31 (20/11) | 30 (15/15) | 28 (14/14) | 1139 (566/573) |
| Live birth | 597 (309/288) | 2 (1/1) | 4 (2/2) | 1 (0/1) | 590 (306/284) |
| Any pregnancy loss | 188 (96/92) | 29 (19/10) | 26 (13/13) | 27 (14/13) | 106 (50/56) |
| Implantation failure | 55 (28/27) | 0 | 0 | 0 | 55 |
| Clinical loss type | 133 (68/65) | 29 (19/10) | 26 (13/13) | 27 (14/13) | 51 (22/29) |
| Pre-embryonic | 36 (17/19) | 7 (4/3) | 4 (1/3) | 8 (4/4) | 17 (8/9) |
| Embryonic | 73 (39/34) | 18 (14/4) | 15 (8/7) | 18 (10/8) | 22 (7/15) |
| Fetal death | 10 (4/6) | 2 (1/1) | 5 (2/3) | 1 (0.1) | 2 (1/1) |
| Stillbirth | 4 (2/2) | 2 (0/2) | 2 (2/0) | 0 | 0 |
| Ectopic | 6 (3/3) | 0 | 0 | 0 | 6 (3/3) |
| Unknown | 4 (3/1) | 0 | 0 | 0 | 4 (3/1) |