Figure 1.

Ischemia pain ratings across the menstrual cycle.

Notes: Women with PMDD rated ischemia pain as more painful during the late-luteal phase, compared to the mid-follicular and ovulatory phases. There was no effect of menstrual phase on ischemia pain ratings for healthy controls (HC). *Indicates a significant difference (P<0.05). The Numerical Rating Scale was used for pain ratings.

Abbreviations: FOL, mid-follicular phase; LUT, late-luteal phase; OVU, ovulatory phase; PMDD, premenstrual dysphoric disorder.