. Author manuscript; available in PMC: 2017 Feb 1.

Published in final edited form as: Respir Med. 2015 Dec 19;111:54–59. doi: 10.1016/j.rmed.2015.12.007

Table 2.

Cross-sectional adjusted associations between CRP and lung function.

	Age 32									Age 38

	Men				Women				Sex interaction	Men				Women				Sex interaction

	n	Est	95% CI	p	n	Est	95% CI	p	p	n	Est	95% CI	p	n	Est	95% CI	p	p
FEV₁	422	−0.073	−0.123, −0.023	0.004	378	−0.056	−0.092, −0.021	0.002	0.446	420	−0.059	−0.117,−0.002	0.043	395	−0.016	−0.053, 0.021	0.389	0.205
FVC	422	−0.104	−0.163, −0.046	0.001	378	−0.040	−0.083, 0.003	0.071	0.029	420	−0.098	−0.166, −0.029	0.006	395	−0.000	−0.045, 0.045	0.989	0.002
FEV₁/FVC	422	0.128	−0.443, 0.698	0.660	378	−0.601	−1.146, −0.056	0.031	0.037	420	0.260	−0.403, 0.923	0.441	395	−0.370	−0.962, 0.222	0.220	0.025
sG_aw^a	414	1.004	0.955, 1.055	0.879	370	0.987	0.947, 1.030	0.553	0.835	418	1.017	0.981, 1.054	0.362	392	0.979	0.953, 1.006	0.134	0.354
TLC^a	413	0.984	0.975, 0.993	0.001	370	0.995	0.986, 1.004	0.270	0.073	417	0.985	0.974,0.996	0.006	393	0.999	0.989, 1.010	0.869	0.082
FRC^a	414	0.984	0.969, 0.998	0.030	370	0.998	0.984, 1.013	0.798	0.004	418	0.974	0.954, 0.994	0.013	393	0.987	0.970, 1.005	0.163	0.027
RV^a	413	0.992	0.973, 1.011	0.427	370	1.004	0.985, 1.024	0.672	0.221	418	0.986	0.965, 1.007	0.192	393	1.003	0.983, 1.024	0.767	0.347
DL_CO^a	421	0.982	0.970, 0.995	0.006	369	0.995	0.982, 1.007	0.394	0.261	413	0.976	0.962, 0.990	0.001	383	0.991	0.978, 1.003	0.148	0.138
DL_CO/V_A	421	−0.004	−0.065, 0.057	0.896	369	0.010	−0.050, 0.069	0.751	0.997	413	−0.028	−0.093, 0.036	0.383	383	−0.025	−0.085, 0.036	0.421	0.916

p values < 0.05 are highlighted in bold.

Log-transformed outcome so estimates and CIs are ratios of geometric means rather than differences of arithmetic means. Log-transformed CRP was used as the independent variable of interest. Analyses are adjusted for height, BMI, and pack years smoking. DL_CO and DL_CO/VA analyses are also adjusted for exhaled carbon monoxide and haemoglobin.