Table 3.
Associations between baseline values of CRP and changes in lung function measures.
n | Estimate | 95% CI | p-value | |
---|---|---|---|---|
FEV1b | 729 | 0.020 | 0.006, 0.034 | 0.005 |
FVCb | 729 | 0.005 | −0.012, 0.021 | 0.586 |
FEV1/FVCb | 729 | 0.340 | 0.130, 0.550 | 0.002 |
sGawa | 716 | 0.994 | 0.980, 1.007 | 0.353 |
TLCa,b | 714 | 1.001 | 0.998, 1.004 | 0.358 |
FRCa,b | 716 | 0.997 | 0.989, 1.006 | 0.581 |
RVa | 715 | 0.996 | 0.985, 1.006 | 0.384 |
DLCOa | 698 | 1.002 | 0.997, 1.008 | 0.409 |
DLCO/VA | 698 | 0.023 | −0.003, 0.049 | 0.088 |
p values < 0.05 are highlighted in bold.
Log-transformed outcome so estimates and CIs are ratios of geometric means rather than differences of arithmetic means. Log-transformed CRP was used as the independent variable of interest Analyses are adjusted for sex, height, changes in BMI and pack years smoking between ages 32 and 38 years. DLCO and DLCO/VA analyses are also adjusted for changes in exhaled carbon monoxide and haemoglobin.
Sex-BMI interaction included in the model.