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. 2015 Nov 30;7(2):1447–1456. doi: 10.1039/c5sc03798k

Fig. 2. Epimerization of GlcA to IdoA by DS-epi1 conducted in D2O (modified from16). First, a hydrogen on C5 of GlcA is removed by His450 of DS-epi1. Next, a deuterium is incorporated from His205 of DS-epi1 into an intermediate product (not shown), generating IdoA.

Fig. 2