Table 4. Combined rate of cure and probable cure at 24 months.
Pafuramidine | Pentamidine | 95% CIa | |
---|---|---|---|
100 mg BID | 4 mg/kg QD | ||
n/N (%) | n/N (%) | ||
Per-protocol population | 113/135 (83.7) | 116/130 (89.2) | -2.7, 13.7 |
ITT population | 113/136 (83.1) | 116/137 (84.7) | -7.1, 10.3 |
mITT population | 114/136 (83.8) | 123/137 (89.8) | -2.0, 14.0 |
BID = twice a day, CI = confidence interval, ITT = intent-to-treat population, mITT = modified intent-to-treat population, QD = once a day
a Confidence intervals based on normal approximation to the binomial for pentamidineāpafuramidine