Table 4. Demographic and clinical characteristics of subjects with severe mental illness by class of antipsychotic medication in subjects on monotherapy.
| Subjects taking FGAs (n = 32) | Subjects taking SGAs (n = 95) | p | |
|---|---|---|---|
| Gender | 0.7 a | ||
| Male | 65.6(21) | 69.5(66) | |
| Female | 34.4(11) | 30.5(29) | |
| Age (years) | 33.7 ±13.8 | 33.3 ± 12.3 | 0.9 b |
| Diagnosis | 0.5 a | ||
| Schizophrenia | 96.9(31) | 88.4(84) | |
| Schizoaffective disorder | 3.1 (1) | 9.5 (9) | |
| Bipolar mood disorder | 0(0) | 2.1 (2) | |
| Body Mass Index (BMI) (kg/m2) | 26.6 ± 7.57 | 27.5 ± 6.31 | 0.5 b |
| BMI category: | 0.5 a | ||
| Normal: < 25 | 59.3(19) | 47.4(45) | |
| Overweight: 25–29.9 | 18.8(6) | 23.2(22) | |
| Obese: >30 | 21.9(7) | 29.5(28) | |
| Waist circumference (cm) | 90.5 ± 15.4 | 92.3 ± 16 | 0.6 b |
| Blood pressure (mmHg): | |||
| Systolic | 119.2 ± 11.3 | 122.5 ±17.9 | 0.3 b |
| Diastolic | 72.6 ± 8.5 | 76.6 ± 10.2 | 0.04 b |
| Fasting plasma glucose (mmol/l) | 5.2 ± 1.3 | 5.3 ± 1.4 | 0.7 b |
| Serum Lipids (mmol/l): | |||
| Total cholesterol | 4.2 ± 1.1 | 4.2 ±1.1 | 0.7 b |
| Total triglycerides | 0.9 ± 0.4 | 1.1 ± 0.7 | 0.08 b |
| High Density Lipoprotein cholesterol | 1.2 ± 0.3 | 1.1 ± 0.3 | 0.2 b |
| Low Density Lipoprotein cholesterol | 2.6 ± 1.0 | 2.6 ±0.9 | 0.7 b |
Data are mean ± SD and % (n), unless otherwise indicated. FGA: first generation antipsychotic, SGA: second generation antipsychotic.
a Fisher’s exact test,
b Student’s t—test.