Table 2. Generalized estimating equations (GEE) evaluating associations of interact time and groups with respiratory rates and heart rates of the HFMD patient.
| Variables | Mean (95% CI) | P1 value | P2 value | P3 value | P4 value |
|---|---|---|---|---|---|
| Respiratory rates (times/min) | |||||
| Groups | |||||
| Control | 29.73 (29.01, 30.46) | Reference | |||
| Ultrasonic aerosol inhalation | 28.69 (28012, 29.25) | 0.029 | Reference | ||
| Intramuscular injection | 31.08 (30.49, 31.67) | 0.005 | <0.001 | ||
| Time | |||||
| First day | 32.60 (31.83, 33.36) | Reference | |||
| Second day | 32.46 (31.63, 33.30) | 0.820 | Reference | ||
| Third day | 30.08 (29.23, 30.92) | <0.001 | <0.001 | Reference | |
| Fourth day | 27.52 (26.68, 28.37) | <0.001 | <0.001 | <0.001 | Reference |
| Fifth day | 26.51 (25.65, 27.36) | <0.001 | <0.001 | <0.001 | 0.098 |
| Heart rates (times/min) | |||||
| Groups | |||||
| Control | 129.86 (120.33, 139.38) | Reference | |||
| Ultrasonic aerosol inhalation | 126.31 (121.08, 131.55) | 0.528 | Reference | ||
| Intramuscular injection | 132.82 (126.77, 138.87) | 0.608 | 0.111 | ||
| Time | |||||
| First day | 129.73 (128.23, 131.22) | Reference | |||
| Second day | 140.19 (125.12, 155.26) | 0.171 | Reference | ||
| Third day | 127.18 (125.80, 128.57) | 0.014 | 0.090 | Reference | |
| Fourth day | 127.08 (117.17, 137.00) | 0.608 | 0.152 | 0.985 | Reference |
| Fifth day | 124.13 (115.20,133.06) | 0.228 | 0.072 | 0.513 | 0.665 |