Skip to main content
. Author manuscript; available in PMC: 2016 Mar 17.
Published in final edited form as: Neurosci Lett. 2015 Jan 28;590:134–137. doi: 10.1016/j.neulet.2015.01.064

Fig. 1.

Fig. 1

Chromatographic confirmation of monoamine aldehyde production from monoamines by MAO-A (A, B) and alpha-synuclein (AS) oligomerization evoked by the aldehydes (C). (A) Conversion of dopamine (DA) to 3,4-dihydroxyphenylacetaldehyde (DOPAL) upon incubation of DA with MAO-A, (B) Conversion of serotonin (5HT) to 5-hydroxyindolealdehyde (5-HIAL) upon incubation of the 5HT with MAO-A. (C) Western blotting of alpha-synuclein oligomers produced by incubating DA or 5HT with MAO-A. The oligomerization was prevented by pargyline (PAR). Histogram shows mean (±SEM) values. (*) indicates p < 0.01 vs. control, (**) indicates p < 0.001 vs. control) and (#) indicates p < 0.001 compared to no PAR.