Table 2. Comparison of the coculture conditions with various origins of hMSCs feeder.
Article | Source of feeder | Culture condition | hPSCs | hPSCs passages | Teratoma formation |
---|---|---|---|---|---|
This report | human umbilical cord stroma | xeno-free medium | hiPSCs | over 30 | Yes |
Ma et al.[37] | human amniotic fluid | DMEM + 10% FBS | hESCs (X-01) | over 30 | Yes |
Fukusumi et al. [38] | human decidua | DMEM/F-12 + 10% FBS | hiPSCs | 10–20 | Yes |
Soong et al. [39] | human amniotic fluid | IMDM + 15% FBS | hESCs | 14–22 | Yes |
Havasi et al. [40] | human bone marrow | DMEM-low glucose + 10% FBS | hiPSCs | 20 | ND |
Zhang et al. [41] | human bone marrow | DMEM-low glucose + 10% FBS | hiPSCs | 14–16 | Yes |
Ding et al. [23] | human umbilical cord stroma | DMEM-low glucose + 10% CBS | hESCs (TW1) | over 20 | No |
Cho et al. [42] | human umbilical cord stroma | DMEM + 20% FBS | hESCs (H9) | 20 | Yes |
Cheng et al. [43] | human bone marrow | DMEM-low glucose + 10% FBS | hESCs (H1) | under 13 | ND |
FBS: fetal bovine serum; CBS: human umbilical cord blood serum; ND: not determined because teratoma formation didn’t be mentioned in these reports.