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. 2016 Feb 16;11(2):e0148577. doi: 10.1371/journal.pone.0148577

Table 1. Differentially regulated lipids between aged and young oocytes.

Fold change ≥ 1.5 (p < 0.05).

Upregulated lipids in aged oocytes (6) Downregulated lipids in aged oocytes (26)
Assignment Precursor Ion Product Ion p-value Ratio* Assignment Precursor Ion Product Ion p-value Ratio*
TG(56:7) 922.79 577.5 0.004 2.162 PI(36:0)** 881.6 607.3 0.043 0.213
PE(36:4) 740.4 599.3 0.007 1.607 LPE(18:2) 478.3 337.2 0.000 0.242
hE(20:4) 690.6 369.2 0.009 1.588 PI(32:0)** 825.6 551.3 0.000 0.272
PC(36:4) 782.5 183.9 0.018 1.851 PI(34:0)** 853.6 579.3 0.033 0.291
PC(36:5) 780.5 183.9 0.024 1.959 PI(34:1)** 851.6 577.3 0.000 0.324
PC(38:5) 808.5 183.9 0.046 1.548 PI(36:2)** 877.6 603.3 0.033 0.327
PI(34:2)** 849.6 575.3 0.008 0.350
TG(60:3) 986.82 603.5 0.048 0.354
PA(28:5)** 611.5 485.3 0.004 0.425
LPS(18:0)** 554.3 341.2 0.029 0.444
PA(30:1)** 647.5 521.3 0.017 0.479
DG(34:0) 614.5 579.5 0.026 0.494
PA(28:4)** 613.5 487.3 0.002 0.511
dCer1P(d14:1–20:5)** 638.5 210.1 0.001 0.511
PA(30:3)** 643.5 517.3 0.030 0.524
PA(30:0)** 649.5 523.3 0.001 0.531
PA(32:3)** 671.5 545.3 0.000 0.541
DG(32:0) 586.5 551.5 0.020 0.568
SO(d14:1) 244.3 208.1 0.003 0.577
PE(36:3) 742.4 601.3 0.008 0.579
LPC(18:2) 520.1 183.9 0.022 0.581
PS(28:0)** 708.6 495.3 0.005 0.588
LPS(22:6)** 598.3 385.2 0.009 0.595
LPS(18:1)** 552.3 339.2 0.016 0.632
PS(36:1)** 818.6 605.3 0.022 0.638
Cer1P(d18:1–16:1)** 644.5 264.1 0.004 0.654

* Ratio, aged oocytes/young oocytes

** Acidic lipids analyzed after TMSD derivatization.