. 2016 Feb 16;10(2):e0004362. doi: 10.1371/journal.pntd.0004362

Table 4. Parasitological cure rates (primary and secondary efficacy endpoints).

	Phase 2a Pafuramidine 100 mg BID 5 days N = 32	Phase 2b		Phase 2b-2 Pafuramidine 100 mg BID 10 days N = 30
		Pafuramidine 100 mg BID 5 days N = 40	Pentamidine 4 mg/kg QD 7 days N = 41
24 hours	93% (27/29)^a	ND	ND	ND
3 months	93% (26/28)	79% (31/39)^a	100% (40/40)^a	93% (26/28)^a
6 months	85% (23/27)	82% (31/38)	97% (38/39)	84% (21/25)
12 months	79% (19/24)	83% (30/36)	94% (34/36)	84% (21/25)
24 months	67% (14/21)	82% (27/33)	97% (31/32)	90% (19/21)

BID = twice a day; QD = once daily; ND = not determined

^a Primary efficacy endpoint