a. Drop-one SNV and drop-one cohort for genome-wide significant 30 SNV windows for forearm BMD from skatMeta analysis. (A, B) For given 30 SNV window, the –log10(p) of skatMeta test for 29 SNVs, excluding (i.e. dropping) the SNV at position labeled on x-axis. (C, D) For given 30 SNV window, the –log10(p) of skatMeta test for 4 cohorts, excluding (i.e. dropping) cohort labeled on x-axis. b. Drop-one SNV and drop-one cohort for genome-wide significant 30 SNV windows for femoral neck BMD for skatMeta analysis. (A) For given 30 SNV window, the –log10(p) of skatMeta test for 29 SNVs, excluding (i.e. dropping) the SNV at position labeled on x-axis. (B) For given 30 SNV window, the –log10(p) of skatMeta test for 4 cohorts, excluding (i.e. dropping) cohort labeled on x-axis. c. Regional view of CPED1/WNT16 locus for forearm BMD. In top panel, significant SNVs from single variant meta-analysis (rs148771817 and rs79162867, in blue) overlap significant regions found using region-based test (red bars).