Figure 7. Similarity-based prediction error responses in the hippocampus during generalization.
(A) Across both groups, activity in the hippocampus is significantly correlated with model-derived prediction errors during generalization test. T-map from one-sample t-test is thresholded at P < 0.05, FWE whole brain corrected and overlaid on a T1-weigthed image averaged across subjects. (B) Prediction error-related activity in the hippocampus is significantly reduced by D2R blockade (two-sample t-test, t = -2.12, P = 0.02). Error bars are SEM for N = 25 (PA) and N = 21 (PP).