Video 2. Lipid droplet (LD) enlargement induced by CIDEA.
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DOI: 10.7554/eLife.07485.005
LD dynamics in undifferentiated 3T3-L1 cells 6 hr after infection with adenoviral particles carrying the mouse Cidea gene. After CIDEA induction, the initial individual LDs form stable contacts reflected by small irregularly shaped clusters of LDs. These interacting LDs undergo an enlargement process by lipid transference, characterized by the progressive enlargement of the acceptor LD and shrinkage of the donor LD until only a few large LDs remain in the cell.