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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Neuropharmacology. 2015 Dec 22;103:279–289. doi: 10.1016/j.neuropharm.2015.12.016

Fig. 1. Putative p38 MAPK phosphorylation sites are highly conserved in the Slack C-terminus across species.

Fig. 1

Amino acid sequence alignment of the mammalian (rSlack- rat, hSlack- human, mSlack- mouse, cSlack- chicken), Xenopus (xSlack) and Zebrafish (zSlack) Slack channel. Serines at positions 736 and 742 (black, underlined) in the RCK2 domain of Slack are the putative p38 phosphorylation motifs, and are evolutionarily conserved across species. Also shown in red is the putative Na+ binding site in close proximity.