Skip to main content
. Author manuscript; available in PMC: 2016 Aug 15.
Published in final edited form as: Integr Biol (Camb). 2016 Jan 22;8(2):149–155. doi: 10.1039/c5ib00265f

Figure 3. Trapped chromatin fibers perturb blood flow.

Figure 3

A) NETs (green) released by the activation of human neutrophils upstream and trapped at the entrance of the capillary network, divert the traffic of RBCs (red) flowing through the device. An area void of RBCs extends from one end to the other of the capillary network. B) Whole blood flows through a capillary network with two large obstacles in the middle (rhomboidal areas outlined in yellow). Flow of RBCs through the network is maintained in all areas around and behind the obstacles. Flow is from left to right. The microfluidic devices consist of 10 × 10 μm channels in a hexagonal pattern with 50 μm pitch. Scale bar represents 100 μm.